Effects of Intervention Schemes on Sulphadoxine-Pyrimethamine Compliance Among Pregnant Women in a Health Facility in Port Harcourt, Rivers State, Nigeria

Autor:	A. E. Abah, Florence O. Nduka, Helen Onoja
Rok vydání:	2021
Předmět:	education.field_of_study Fetus medicine.medical_specialty Obstetrics business.industry Birth weight Population medicine.disease Low birth weight Health facility Intervention (counseling) medicine medicine.symptom Adverse effect education business Malaria
Zdroj:	International Journal of Infection. 8
ISSN:	2383-1421 2383-1413
DOI:	10.5812/iji.107940
Popis:	Background: Malaria causes diverse adverse effects in the fetus due to the invasion of the placenta by Plasmodium. The use of intermittent preventive treatment (Sulphadoxinepyrimethamine- IPTp-SP) as a control measure for malaria in pregnancy has been recommended and shown to reduce unwanted birth outcomes. Objectives: This work aimed to evaluate the effects of intervention schemes on sulphadoxine-pyrimethamine (SP) compliance and utilization among pregnant women in a health facility in Port Harcourt, Nigeria. Methods: A hospital-based survey was carried out among pregnant women admitted to the Labor ward of Obio-Cottage hospital. The information of mothers was collected using a well-structured and pre-tested questionnaire and from their antenatal care (ANC) records. Results: Time of ANC registration indicated that 87%, 11.33%, and 1.66% of mothers were registered during their first, second, and third trimesters, respectively. Sulphadoxinepyrimethamine was the drug of choice for 93.66% of the women while 6.33% took other drugs. The survey revealed that 97.15% and 2.85% of the women started SP usage in their second and third trimesters, respectively. It was observed that the majority of the women (69.39%) took SP thrice while 24.19% and 6.40% consumed it twice and once, respectively. Regarding knowledge about SP, 89% of the women viewed SP as a preventive drug for malaria while 11% acknowledged it as a therapeutic drug. The birth outcomes of the neonates whose mothers took SP indicated that 1.42% had low birth weight (LBW) while 98.57% had acceptable birth weight. Meanwhile, 10.53% of the babies born to the mothers who did not use SP had LBW, and 89.47% of them had acceptable birth weights. Overall, 98.93% of the neonates of SP-compliant women and 89.48% of the babies of non-compliant women were alive. Non- compliant women had higher prevalence of preterm birth (5.76%) and fetal death (5.26%) than SP-compliant women (0.7% and 0.35%, respectively). Conclusions: Adequate knowledge and compliance with SP usage were high in the studied population, which was associated with favorable birth outcomes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d8b7b4cd8ddc7ae26650207a7884631f https://doi.org/10.5812/iji.107940 Zobrazit plný text záznamu