Mammary Gland
| Autor: | Pamela E. Blackshear, Alok K. Sharma, Johnnie J. Eighmy |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
040301 veterinary sciences
Mammary gland Focal hyperplasia Physiology Cancer 04 agricultural and veterinary sciences Rat Mammary Gland Biology medicine.disease 030226 pharmacology & pharmacy Fibroadenoma 0403 veterinary science 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Toxicity medicine Adenocarcinoma sense organs skin and connective tissue diseases Hormone |
| DOI: | 10.1016/b978-0-12-391448-4.00021-6 |
| Popis: | The rat mammary gland has been studied extensively as a model for cancer. Factors such as the strain of rat, age, parity, hormones, and diet must all be considered in the proper interpretation of apparent increases in mammary gland neoplasms following exposure to chemicals, radiation, or environmental agents. Nonneoplastic mammary gland changes are also seen in rats. These nonneoplastic changes include degenerative, inflammatory, vascular, hyperplastic, miscellaneous, and toxicologic changes. The accurate assessment of mammary gland changes and understanding their importance is critical, particularly when evaluating drug-related toxicity and carcinogencity. |
| Databáze: | OpenAIRE |
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