| Autor: |
Jiayan Zhang, Hui Chen, Xingjie Dai, Wei-Cheng Yuan, Xiao-Mei Zhang, Shuowen Yu, Xiao-Ying Xu, Wang Zhouyu, Shaobing Cheng, Guanglin Weng |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Organic Chemistry Frontiers. 5:2787-2793 |
| ISSN: |
2052-4129 |
| DOI: |
10.1039/c8qo00602d |
| Popis: |
A one-pot diastereo- and enantioselective hydrosilylation–transacylation of N-unprotected α-acyloxy β-enamino esters was realized. By using an easily accessible novel chiral Lewis base as a catalyst, this transformation allowed for the direct synthesis of highly enantioenriched α-hydroxyl-β-acylamido esters (up to >20 : 1 dr and 99% ee). The absolute configurations of two products were assigned by comparison of the optical rotations with the literature and the absolute configurations of other products were determined accordingly. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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