Chronic Mucocutaneous Candidiasis in Humans With Inborn Errors of Interleukin-17 Immunity
| Autor: | James E. Gern, Douglas F. McMahon |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
biology
business.industry Disease medicine.disease_cause medicine.disease biology.organism_classification Staphylococcal infections Oropharyngeal Candidiasis Immunity Pediatrics Perinatology and Child Health Immunology Medicine Interleukin 17 Chronic mucocutaneous candidiasis business Candida albicans Staphylococcus |
| Zdroj: | Pediatrics. 128:S140-S141 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2011-2107cccc |
| Popis: | A Puel, S Cypowyj, J Bustamante. Science. 2011;332(6025):65–68 Chronic mucocutaneous candidiasis disease (CMCD) is characterized by recurrent or persistent infections of the skin, nails, and oral and genital mucosa caused by Candida albicans and sometimes Staphylococcus . Previous studies have shown that interleukin 17 (IL-17) receptor-deficient mice were more susceptible to oropharyngeal candidiasis and staphylococcal infections of the skin. The purpose of this study was to assess if findings in the mouse model also applied to humans. Candidate gene sequencing was performed on a child … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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