Relative pressure estimation from velocity measurements in blood flows: State-of-the-art and new approaches
| Autor: | Rodolfo Nuñez, Felipe Galarce, Cristóbal Bertoglio, Axel Osses, David Nordsletten |
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| Rok vydání: | 2017 |
| Předmět: |
Computer science
Applied Mathematics Spatially resolved Acoustics Biomedical Engineering Gold standard (test) 030204 cardiovascular system & hematology Synthetic data 030218 nuclear medicine & medical imaging 03 medical and health sciences Noise 0302 clinical medicine Computational Theory and Mathematics Modeling and Simulation Compressibility Relative pressure Sensitivity (control systems) Navier–Stokes equations Molecular Biology Software Simulation |
| Zdroj: | International Journal for Numerical Methods in Biomedical Engineering. 34:e2925 |
| ISSN: | 2040-7939 |
| DOI: | 10.1002/cnm.2925 |
| Popis: | The relative pressure difference across stenotic blood vessels serves as an important clinical index for the diagnosis of many cardiovascular diseases. While the clinical gold standard for relative pressure difference measurements is invasive catheterization, Phase-Contrast Magnetic Resonance Imaging has emerged as a promising tool for enabling a noninvasive quantification, by linking highly spatially resolved velocity measurements with relative pressures via the incompressible Navier-Stokes equations. In this work, we provide a review and analysis of current methods for relative pressure estimation and propose 3 additional techniques. Methods are compared using synthetic data from numerical examples, and sensitivity to subsampling and noise was explored. Through our analysis, we verify that the newly proposed approaches are more robust with respect to spatial subsampling and less sensitive to noise and therefore provide improved means for estimating relative pressure differences noninvasively. |
| Databáze: | OpenAIRE |
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