Zwei einfache Fragen zur Diagnose der Post-Schlaganfall Depression

Autor: Christian H. Nolte, Karin Rossnagel, Arno Reich, Inga Laumeier, Gerhard J. Jungehulsing, Stephanie Roll, D. Beerfelde, Arno Villringer, Jacqueline Müller-Nordhorn, Stefan N. Willich
Rok vydání: 2006
Předmět:
Zdroj: Fortschritte der Neurologie · Psychiatrie. 74:251-256
ISSN: 1439-3522
0720-4299
DOI: 10.1055/s-2005-919144
Popis: BACKGROUND AND PURPOSE: Many patients develop a depression after having suffered a stroke. Such a Post-Stroke Depression (PSD) impairs rehabilitation and quality of life. PSD is underdiagnosed in spite of available treatment. Several questionnaires have been created to diagnose a PSD. But questionnaires have been considered cumbersome and time-consuming. The aim of this study was to find out whether two simple, standardised questions will identify those stroke patients, who have developed a PSD. METHODS: The two case-finding questions and the Beck Depression Inventory (BDI) were sent to patients of the Berlin Acute Stroke Study (BASS) four years after their stroke. Incomplete questionnaires were complemented via mail or telephone. Severity of depression was assessed by means of BDI. RESULTS: Out of 211 patients, 199 responded to the questionnaire (94 %). 193 questionnaires were complete (97 %). Forty-two patients affirmed both case-finding questions (22 %). Compared to patients, who did not affirm both questions, these patients had a higher BDI score (19 +/- 8 vs. 7 +/- 5; p < 0.001). The sensitivity and specificity of the two questions were 89 % and 90 %, respectively. The positive and negative predictive value were 60 % and 98 % respectively. The number of confirmed questions (0, 1, 2) correlated well with the BDI score (r (2) = 0.67, p < 0.001). CONCLUSIONS: Two standardized questions can identify patients with PSD for further diagnostic evaluation and therapy. Diagnosis of PSD might be facilitated by using them as screening instrument.
Databáze: OpenAIRE