Engineered biomimetic nanoabsorbent for cellular detoxification of chemotherapeutics

Autor: Santosh Aryal, Faqir Muhammad, Tuyen Duong Thanh Nguyen, Mukund Bahadur Koirala, Arunkumar Pitchaimani
Rok vydání: 2016
Předmět:
Zdroj: RSC Advances. 6:33003-33008
ISSN: 2046-2069
DOI: 10.1039/c6ra02026g
Popis: An approach to reduce the nonspecific cytotoxicity of chemotherapeutics has been put-forth using a biomimetic nanoabsorbent (NAb) as a detoxifying agent. The engineered NAb possesses a tunable drug absorption ability depending on the charge of the absorbing molecule, in which the cooperative absorption ability of the core and shell significantly reduces the cellular toxicity.
Databáze: OpenAIRE