Stem Cell Therapy: A Future Treatment of Stress Urinary Incontinence
Autor: | Malgorzata Stec, Klaudia Stangel-Wójcikiewicz, Michael B. Chancellor, Dmitriy Nikolavasky |
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Rok vydání: | 2011 |
Předmět: |
medicine.medical_specialty
Urinary continence business.industry Endocrinology Diabetes and Metabolism medicine.medical_treatment Urology Obstetrics and Gynecology Urinary incontinence Stem-cell therapy Surgery Cell therapy Endocrinology Reproductive Medicine Physiology (medical) medicine Myocyte Rhabdosphincter Stem cell medicine.symptom business Adult stem cell |
Zdroj: | Seminars in Reproductive Medicine. 29:061-070 |
ISSN: | 1526-4564 1526-8004 |
DOI: | 10.1055/s-0030-1268705 |
Popis: | The main urinary continence mechanism in human is the striated muscle rhabdosphincter that forms a ring around the mid-urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence (SUI) may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells. |
Databáze: | OpenAIRE |
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