| Autor: |
Geoffroy Canlorbe, Xavier Carcopino, Emilie Raimond, Lobna Ouldamer, Alexandre Bricou, Cyrille Huchon, Lise Lecointre, Ludivine Dion, Pierre Collinet, Marcos Ballester, Vincent Lavoué, Tiphaine de Foucher de Careil, François Golfier, Clémentine Owen, Yohan Kerbage, Cecile Hennebert, Groupe de Recherche Francogyn, Pierre Adrien Bolze, Sofiane Bendifallah, Cherif Akladios, Emile Daraï, Olivier Graesslin, Cyril Touboul, Y. Dabi |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
SSRN Electronic Journal. |
| ISSN: |
1556-5068 |
| DOI: |
10.2139/ssrn.3675395 |
| Popis: |
Background: The standard of care for patients with advanced cervical cancer (ACC) includes platinum-based chemotherapy. The concept of platinum sensitivity is a major prognostic factor for patients with ovarian cancer. The aim of this study was to validate the applicability of the platinum sensitivity concept to ACC patients, and to estimate its prognostic interest in term of Overall Survival (OS) and pattern of recurrence (location, timing). Methods: Data of women with histologically proven FIGO 2019 stages IB3-IV ACC treated between May 2000 and November 2017 with platinum based regimens were retrospectively abstracted from 12 institutions from the FRANCOGYN Group. Findings: Respective 3-year OS were 52% (95% CI: 40·8-66·8), 21·6% (95% CI: 12·6-37·2) and 14·6% (95% CI: 4·2-50·2), in case of recurrence 18 months (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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