Speed of Onset of Regional Analgesia in Labour: A Comparison of the Epidural and Spinal Routes

Autor: N. K. Lillywhite, B. Loughnan, D. J. A. Vaughan, M. Hasan, P. N. Robinson, J. S. Nickells
Rok vydání: 2000
Předmět:
Zdroj: Obstetrical & Gynecological Survey. 55:543-544
ISSN: 0029-7828
Popis: This study compares the speed of onset of effective analgesia in two randomly assigned groups of patients requesting analgesia in labour. Patients in the combined spinal-epidural group (n = 69) were given a subarachnoid injection of 1.5 ml containing bupivacaine 2.5 mg and fentanyl 25 microg for initiation of analgesia. Patients in the epidural group (n = 73) were given an epidural injection of 10 ml containing bupivacaine 12.5 mg and fentanyl 50 microg. Mean (SD) onset times to the first pain-free contraction were 10.0 (5.7) min in the combined spinal-epidural group and 12.1 (6.5) min in the epidural group (p = 0.054). Patients in the combined spinal-epidural group suffered a higher incidence of motor weakness and proprioceptive deficit than those in the epidural group (p = 0.01). The incidence of technique failure and side-effects was similar in the two groups. It is our contention that the statistically nonsignificant difference in onset times does not justify the additional potential for side-effects and the extra cost of the equipment involved in the combined spinal-epidural technique.
Databáze: OpenAIRE