K2CO3/NaI-Induced Cyclization of ω-Bromo α-Cyano Ketones: A New Annulation Approach for the Formation of Carbalkoxycyclohexane Ring System

Autor:	Min-Tsang Hsieh, Kak-Shan Shia, Sheng-Chu Kuo, Che-Hao Tu, Hsing-Jang Liu
Rok vydání:	2012
Předmět:	Annulation Bicyclic molecule Chemistry Organic Chemistry Michael reaction Ring (chemistry) Combinatorial chemistry
Zdroj:	Synlett. 23:1653-1656
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0031-1290386
Popis:	An operationally simple and highly effective annulation process, making use of ZnCl2-catalyzed Michael addition and K2CO3/NaI-induced cyclization as key manipulations, has been developed to construct various bicyclic systems with a high level of functionalization valuable for further synthetic elaboration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d868db98e78e79f4c47a1b1cb543fc97 https://doi.org/10.1055/s-0031-1290386 Zobrazit plný text záznamu