Oxi-Inflammatory Stress and Biomolecular Deterioration: A Mysterious Convergence in Post COVID Patients
| Autor: | null Rahul Saxena, null Suyash Saxena, null Ajit Pal Singh, null Vandana Singh, null Babita, null Jyoti Batra |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Pharmaceutical Negative Results. :555-561 |
| ISSN: | 2229-7723 0976-9234 |
| DOI: | 10.47750/pnr.2022.13.s06.077 |
| Popis: | Background: Despite several scientific efforts against COVID 19, conundrum of biomolecular deterioration in Post COVID syndrome patients are still in dark at an unprecedented scale globally and affected the patient’s health multidimensionally. It is conceivable that patients recovered from COVID-19 after second wave are at enhanced risk of secondary complications.Aim: The present study was carried out to estimate the serum vitamin D and total antioxidant activity (TAC) along withmarkers of oxi-inflammatory stress in post COVID patients diagnosed RT-PCR negative after second wave of COVID-19 andto determine their role in predicting secondary complications.Methodology: 50 subjects (30-55 years) of Delhi-NCR region were recruited and categorized into two groups (n=25 in each group; on the basis of their history of COVID infection). By using standard methods, study group parameters were estimated in Post COVID patients and statistically compared it with that of 25 non affected healthy controls by using student’s t-test.Result: Serum CRP, TNF-α, MDA and uric acid levels were significantly high (p |
| Databáze: | OpenAIRE |
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