Molecular Markers for Throat and Skin Isolates of Group A Streptococci

Autor: Debra E. Bessen, Susan K. Hollingshead, Therese R. Fiorentino
Rok vydání: 1997
Předmět:
Zdroj: Streptococci and the Host ISBN: 9781489918277
DOI: 10.1007/978-1-4899-1825-3_125
Popis: The nasopharyngeal mucosa and impetigo lesion serve as the primary sites of infection and principal reservoirs for transmission of group A streptococci. It has long been recognized that there exists discrete populations of group A streptococci that are associated with either the throat or skin, and it is the M protein serotype that defines the so-called throat and skin strains (1,9). The M and M-like family of proteins form surface fibrils which display structural and functional diversity. One of our goals has been to trace the molecular pathway that links pathogenic properties to epidemiological markers. As a first step, we sought to better understand the organization that underlies the complex emm gene family.
Databáze: OpenAIRE