ORAL MANIFESTATION OF DIFFUSE LARGE B-CELL LYMPHOMA

Autor: Manoela Domingues Martins, Vinicius Coelho Carrard, Luan Nathiel Santana Kovalski, Michelle Roxo-Gonçalves, Marina Girardi Schueigart, Juliana Romanini, Luis Rivero
Rok vydání: 2020
Předmět:
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e35
ISSN: 2212-4403
DOI: 10.1016/j.oooo.2019.06.098
Popis: A 45-year-old man presented with an extensive gingival growing disseminated in the jaws, leading to limitations with eating, talking, and mouth closure. The diagnostic hypothesis was lymphoma. A test for human immunodeficiency virus (HIV) was positive. An incisional biopsy was performed and histopathologic analysis was compatible with lymphocytic malignant neoplasm (unspecified). At subsequent immunohistochemical analysis, a diagnosis of diffuse large B-cell lymphoma was rendered. The patient was referred to a hematologist and started on chemotherapy. Initially, a significant clinical improvement was seen and the patient remains under treatment. The patient is in clinical and radiographic control, without mouth lesions. The World Health Organization classifies lymphomas into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL). Based on morphologic aspects and immunohistochemistry, these tumors may be classified as B-cell, T-cell, and natural killer cell type. The B-cell origin comprises about of 85% of lymphomas and presents immunoreactivity for markers like CD20 and CD79a.
Databáze: OpenAIRE
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