Syntheses of Methyl 2-O-, 3-O- and 6-O-(2′-Hydroxypropyl)-α-D-Glucopyranosides1

Autor:	Ansui Xu, Paul A. Seib, Lixian Gan
Rok vydání:	1997
Předmět:	Chemistry Organic Chemistry Diastereomer Biochemistry Medicinal chemistry
Zdroj:	Journal of Carbohydrate Chemistry. 16:155-164
ISSN:	1532-2327 0732-8303
DOI:	10.1080/07328309708006517
Popis:	Methyl 6-O-, 3-O- and 2-O-(2′-hydroxypropyl)-α-D-glucopyranosides (4,8, and 12) were synthesized starting from methyl 2,3,4-tri-O-benzyl-α-D-glucopyranoside (1), methyl 4,6-O-benzylidene-α-D-glucopyranoside (5), and methyl 3-O-benzyl-4,6-O-benzylidene-D-glucopyranoside (9), respectively. Overall yields were 88%, 6% and 26% of 4, 8 and 12, respectively, with the 2-ether (12) being crystalline and the 3-ether (8) a single diastereomer. 1. This is Contribution No. 96-387-5 from the Kansas Agricultural Experiment Station.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d862ac75a8a803a381f9c1e9b2759db0 https://doi.org/10.1080/07328309708006517 Zobrazit plný text záznamu