| Autor: |
Mario J.A. Saad, Manoel Carneiro Oliveira-Junior, Milton A. Martins, BreAnne MacKenzie, Ana Paula Ligeiro de Oliveira, Ana Roberta Almeida-Oliveira, Aurelia Aparecida Britto, Jefferson Comin Jonco Aquino-Junior, Rodolfo de Paula Vieira, Maysa Alves Rodrigues Brandão-Rangel, Dioze Guadagnini, Luiz O. Leiria, Fernanda Magalhães Arantes-Costa, Nilsa Regina Damaceno-Rodrigues |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
1.2 Rehabilitation and Chronic Care. |
| DOI: |
10.1183/13993003.congress-2016.pa1576 |
| Popis: |
A growing number of studies have shown that obesity induces airway hyperresponsiveness (AHR). AHR is a hallmark of asthma and several studies show a relation between obesity and development of asthmatic phenotype. Moderate intensity aerobic training (AT) inhibits asthma phenotype in experimental models of asthma, but the effects of AT on pulmonary response in a model of diet-induced obesity are unknown. Thus, 80 C57Bl/6 male mice were distributed in Control Lean (CL), Exercise Lean (EL), Obese (O) and Obese+Exercise (OE) groups (n=20). Obesity was induced by a classical model of diet-induced obesity (DIO) using high fat and hypercaloric diet. Treadmill aerobic training was performed for 4 weeks after the establishment of obesity and DIO remained during the whole protocol. The results demonstrated that AT reduced DIO-induced AHR for 25mg/mL (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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