ChemInform Abstract: Iodine-Catalyzed Three-Component One-Pot Synthesis of Naphthopyranopyrimidines under Solvent-Free Conditions

Autor: B. V. Subba Reddy, G. Narasimhulu, Suggala Venkata Satyanarayana, K. Praveen Kumar, P. Lakshmi Reddy, Narender Ravirala
Rok vydání: 2012
Předmět:
Zdroj: ChemInform. 43
ISSN: 0931-7597
DOI: 10.1002/chin.201230192
Popis: Iodine is found to be a highly efficient catalyst for the three-component coupling (3CC) of aldehydes, β-naphthol, and 1,3-dimethylbarbituric acid under solvent-free conditions to afford the corresponding 8,10-dimethyl-12-aryl-12 H -naphtho[1′,2′5,6]pyrano[2,3- d ]pyrimidine-9,11-diones in good yields with high selectivity. The use of readily available iodine makes this method very simple, convenient, and cost-effective.
Databáze: OpenAIRE