GW29-e0033 Combination of Atorvastatin and Atorvastatin-pretreated Mesenchymal Stem Cells Improves the Cardiac Performance after Acute Myocardial Infarction by Targeting SDF-1/CXCR4 axis
Autor: | Yuejin Yang, Xiaqiu Tian |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Chemokine Stromal cell biology business.industry Atorvastatin Mesenchymal stem cell medicine.disease CXCR4 03 medical and health sciences 030104 developmental biology Sdf 1 cxcr4 biology.protein Cancer research medicine Myocardial infarction Cardiology and Cardiovascular Medicine Receptor business medicine.drug |
Zdroj: | Journal of the American College of Cardiology. 72:C69 |
ISSN: | 0735-1097 |
DOI: | 10.1016/j.jacc.2018.08.401 |
Popis: | The interaction between stromal cell-derived factor 1 (SDF-1) and its receptor chemokine CXC motif receptor 4 (CXCR4) plays a vital role in the engraftment of mesenchymal stem cells (MSCs) in the injured myocardium. Our previous studies have demonstrated that atorvastatin (ATV) could improve the |
Databáze: | OpenAIRE |
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