Abstract P170: Hypertensive Pattern After Kidney Transplantation

Autor: Ekamol Tantisattamo, Possawat Vutthikraivit, Haritha Mopuru
Rok vydání: 2017
Předmět:
Zdroj: Hypertension. 70
ISSN: 1524-4563
0194-911X
Popis: Background: The patterns and factors contributing to post-transplant hypertension are unknown. Methods: Seventy kidney transplant recipients enrolled during a 10-month period were divided into deceased donor renal transplant (DDRT) or living donor renal transplant (LDRT) groups. Risk of development for HTN (SBP ≥140 or DBP ≥90 mmHg) between these 2 groups were compared. Results: There was 50 patients (71.4%) in a DDRT group. Mean age±SEM of the DDRT and LRRT were 52.8±1.7 and 52.3±2.7 years, respectively (p=0.872). Mean pre-transplant SBP and DBP were not significantly different between both groups. DDRT group was at greater risk to develop post-transplant systolic HTN than the LRRT group but not statistically significant (HR 1.145, CI 0.616 - 2.130, p=0.668; Figure 1). However, the risk to develop diastolic HTN was significantly lower in DDRT than LRRT groups (HR 0.506, CI 0.265 - 0.965, p=0.039). The risk of developing post-transplant diastolic HTN were not modified by age ( Conclusion: DRT recipients are at higher risk of developing systolic HTN but lower risk for diastolic HTN in DDRT recipients. This pattern of post-transplant HTN is similar to non-transplant elderly patients, whose pulse pressures are widened. Since there was no difference in mean age between DDRT and LRRT groups, underlying process apart from age may affect post-transplant HTN in DDRT and subsequently poorer renal allograft survival in DDRT than that of LRRT.
Databáze: OpenAIRE