Pigmented epidermotropic breast cancer metastases: A rare variant with a particularly unusual feature

Autor:	Lara Haya-Martínez, Itziar Eraña-Tomás, Luis Requena, María Dolores Mendoza-Cembranos, Juan Torre-Castro, Cristina Moya-Martínez
Rok vydání:	2021
Předmět:	Pathology medicine.medical_specialty Histology Epidermis (botany) business.industry Melanoma Dermatology medicine.disease Pathology and Forensic Medicine Breast cancer Feature (computer vision) medicine Immunohistochemistry Differential diagnosis business Breast carcinoma Infiltration (medical)
Zdroj:	Journal of Cutaneous Pathology. 49:99-102
ISSN:	1600-0560 0303-6987
Popis:	Pigmented epidermotropic breast cancer metastases are a rarity, often clinically misdiagnosed as melanocytic lesions. Histopathologically, they show a dermal proliferation of neoplastic metastatic cells that extend to the overlying epidermis in a pattern identical to that seen in primary Paget disease (PD). Differential diagnosis should be established with entities with a similar presentation, such as pigmented mammary PD and malignant melanoma. Immunohistochemistry may be useful for this purpose. We present a new case of pigmented epidermotropic breast cancer metastases with a particularly unusual feature: the absence of dermal infiltration by neoplastic cells, thus considered as pure epidermotropic metastatic involvement.
Databáze:	OpenAIRE
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