Clinical evidence of parietal cortex dysfunction and correlation with extent of allodynia in CRPS type 1

Autor: Jane Hall, Nigel Harris, Jenny Lewis, Helen Cohen, David R. Blake, Candy McCabe
Rok vydání: 2012
Předmět:
Zdroj: European Journal of Pain. 17:527-538
ISSN: 1090-3801
DOI: 10.1002/j.1532-2149.2012.00213.x
Popis: What's already known about this topic? There is increasing neuroimaging evidence of parietal lobe involvement in CRPS. Severe tactile allodynia and unusual symptoms such as body dysmorphia and finger agnosia have also been documented. - What does this study add? Clinical evidence was found for parietal lobe dysfunction in CRPS. Cortical network dysfunction in CRPS may involve parietal areas, and could provide a rationale explanation for otherwise unusual symptoms and signs. The extent of tactile allodynia correlated with the severity of parietal dysfunction, suggesting a role for maladaptive neuroplasticity.
Databáze: OpenAIRE