Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial
| Autor: | S Giaccari, Gabriele Riegler, G. D’Albasio, V. Annese, D. Valpiani, Renata D'Incà, Piero Vernia, C. Mansi, Giampaolo Bresci, del Retto, Renzo Caprilli, M. Ingrosso, Gisc |
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| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Randomization business.industry Clinical Biochemistry General Medicine medicine.disease Biochemistry Ulcerative colitis Gastroenterology Inflammatory bowel disease law.invention Surgery Clinical trial chemistry.chemical_compound Mesalazine chemistry Randomized controlled trial Refractory law Internal medicine medicine Colitis business |
| Zdroj: | European Journal of Clinical Investigation. 33:244-248 |
| ISSN: | 0014-2972 |
| Popis: | Background The treatment of distal ulcerative colitis, refractory to conventional 5-ASA/steroid treatment, is still a matter of debate. The present study aimed at confirming, with adequate statistical power, previous data indicating the usefulness of topical butyrate and 5-ASA in the treatment of this condition. Design Double-blind, placebo-controlled, multicentre study. A total of 51 patients with distal ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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