Determinants of Vitamin D Levels in Nursing Home Residents
| Autor: | Peggy Krause, Paul J. Drinka, Lori Nest, Brian M. Goodman |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
business.industry Health Policy Ambulatory Status Parathyroid hormone General Medicine medicine.disease Body weight Internal medicine medicine Physical therapy Vitamin D and neurology Sun exposure Geriatrics and Gerontology Nursing homes business General Nursing Kidney disease |
| Zdroj: | Journal of the American Medical Directors Association. 8:76-79 |
| ISSN: | 1525-8610 |
| Popis: | Objective To determine the effect of various doses of vitamin D 2 and D 3 , as well as ambulatory status (a surrogate for sun exposure), on 25-OH-D levels. Design Cross-sectional study with multiple regression analysis. Setting A state veterans home for veterans and their spouses. Participants Three hundred two of 609 eligible residents. Measurements Serum 25-OH-D and parathyroid hormone (PTH) level, supplemental dose of vitamins D 2 and D 3 per kilogram of body weight, and 3 levels of ambulatory status. Results The mean 25-OH-D level was 28.6 + 9.2 ng/mL; 6.6% of subjects had values of 16 ng/mL or below. Thirty-two percent of participants had 25-OH-D levels below 30 ng/mL and PTH elevation based on stage of kidney disease, evidence that the suboptimal 25-OH-D level had physiologic consequences. Residents unable to transfer independently had 25-OH-D levels 1.6 ng/mL lower than those able to transfer independently. A regression analysis performed in residents unable to transfer independently (less likely to be exposed to the sun) demonstrated that the average increase in 25-OH-D level per 100 IU of D 3 in a 70-kg resident was 2.1 ng/mL versus 1.8 ng/mL for vitamin D 2 . Conclusion Nursing home residents should receive at least 800–1000 IU of D 3 per day in an effort to maintain optimal vitamin D levels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|