LATTICE STRUCTURE AND DISTANCE MATRIX OF GENETIC CODE

Autor: Nisha Gohain, Adil Akhtar, Tazid Ali
Rok vydání: 2015
Předmět:
Zdroj: Journal of Biological Systems. 23:485-504
ISSN: 1793-6470
0218-3390
DOI: 10.1142/s0218339015500254
Popis: The genetic code is the rule by which DNA stores the genetic information about formation of protein molecule. In this paper, a partial ordering is equipped on the genetic code and a lattice structure has been developed from it. The codon–anticodon interaction, hydrogen bond number and the chemical types of bases play an important role in the partial ordering. We have established some relations between the lattice structure of the genetic code and physico-chemical properties of amino acids. Taking into consideration the evolutionary importance of base positions in codons we have constructed a distance matrix for the amino acids. Further with a real life example we have demonstrated the relationship between frequently occurring mutations and codon distances.
Databáze: OpenAIRE