Sexual-Dimorphism in Exercise-Induced Beiging and Altered Mitochondrial Function in Inguinal White Adipose Tissue (iWAT) from the Mouse

Autor:	Leslie A. Rowland, Ana B.A. Wagner, Noah B. Prince, Michael F. Hirshman, Brent G. Albertson, Laurie J. Goodyear, Roeland J.W. Middelbeek, Pasquale Nigro, Christiano R. R. Alves
Rok vydání:	2018
Předmět:	Sexual dimorphism business.industry Endocrinology Diabetes and Metabolism Internal Medicine Physiology Adipose tissue Medicine Physical exercise White adipose tissue business Metabolic health
Zdroj:	Diabetes. 67
ISSN:	1939-327X 0012-1797
Popis:	Regular physical exercise has numerous benefits on metabolic health, likely involving adaptations to many tissues, including adipose tissue. There are conflicting reports on the effects of exercise training on adaptations to iWAT and we hypothesized that these discrepancies may stem in part from sex-specific differences. Male and female 10 week old C57BL6/J mice were housed in cages with (trained) or without (sedentary) running wheels for 11 days (n=6-9/sex/experiment). Males performed less voluntary exercise vs. females (56±7 vs. 78±5 km; p Disclosure P. Nigro: None. R. Middelbeek: None. C.R. Alves: None. B.G. Albertson: None. L.A. Rowland: None. A.B. Wagner: None. N.B. Prince: None. M.F. Hirshman: None. L.J. Goodyear: None.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d7a909098f4c36e0ff0a0f501884394b https://doi.org/10.2337/db18-758-p Zobrazit plný text záznamu