ChemInform Abstract: 4-Aryl-2-anilinopyrimidines as Corticotropin-Releasing Hormone (CRH) Antagonists

Autor:	Charles R. Arnold, Steven Culp, Paul J. Gilligan, Dennis R. Chidester, Anthony J. Cocuzza, Lawrence W. Fitzgerald, Frank W. Hobbs, Jerry A. Yarem
Rok vydání:	2010
Předmět:	endocrine system chemistry.chemical_compound Corticotropin-releasing hormone chemistry Stereochemistry Aryl General Medicine Ring (chemistry) hormones hormone substitutes and hormone antagonists Hormone
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
Popis:	A series of 4-aryl-2-(N-ethylanilino)pyrimidines has been synthesized as corticotropin-releasing hormone (CRH) inhibitors. The effect of substitution on each aromatic ring on receptor binding was investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d7a245b4f39c05d9a0c0db2f8ae9938e https://doi.org/10.1002/chin.199932156 Zobrazit plný text záznamu Plný text