Single-Bead Fluorescence Microspectroscopy: Detection of Self-Quenching in Fluorescence-Labeled Resin Beads

Autor:	Bing Yan, and Paul C. Martin, Jumi Lee
Rok vydání:	1998
Předmět:	Quenching (fluorescence) Chromatography Chemistry visual_art visual_art.visual_art_medium General Chemistry Bead Fluorescence
Zdroj:	Journal of Combinatorial Chemistry. 1:78-81
ISSN:	1520-4774 1520-4766
DOI:	10.1021/cc9800069
Popis:	We have characterized two sets of fluorescence-labeled beads with single-bead fluorescence microspectroscopy. Our results demonstrate the possible self-quenching effect on the fluorescence in the resin bead and, therefore, call for a careful selection of fluorophores and a rigorous control of the labeling reaction yield in order to generate labeled beads for combinatorial chemistry and other disciplines.
Databáze:	OpenAIRE
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