| Popis: |
Important cellular functions information can be obtained from decomposing Protein-Protein Interaction Networks (PPIN) into constituent groups (complexes, functional modules). Starting from well-covered model organisms (Yeast), our current e orts are shifting to a complex target organism (Homo Sapiens). It is through statistical techniques and machine learning algorithms that one can proceed with probabilistic steps: assigning unlabelled proteins (classi cation), inferring unknown functions (generalization), weighting interactions (scoring). |
