Seroma formation following axillary dissection for breast cancer: Risk factors and lack of influence of bovine thrombin

Autor:	Donn C. Young, Patricia S. Goodman, William E. Burak, William B. Farrar
Rok vydání:	1997
Předmět:	medicine.medical_specialty business.industry medicine.medical_treatment Breast surgery Lumpectomy General Medicine Modified Radical Mastectomy medicine.disease Surgery surgical procedures operative Breast cancer Oncology Seroma medicine Adjuvant therapy Lymphadenectomy business Mastectomy
Zdroj:	Journal of Surgical Oncology. 64:27-31
ISSN:	1096-9098 0022-4790
DOI:	10.1002/(sici)1096-9098(199701)64:1<27::aid-jso6>3.0.co;2-r
Popis:	Background Seromas of the axillary space following breast surgery can lead to significant morbidity and delay in the initiation of adjuvant therapy. A prospective, randomized study was undertaken to evaluate the effect of bovine spray thrombin on seroma formation following either modified radical mastectomy (MRM) or lumpectomy with axillary dissection (LAD). In addition, risk factors for seroma formation were analyzed and identified. Methods A total of 101 patients were randomized to receive either bovine thrombin (20,000 units) (treatment group) or no thrombin (control group) applied to their axilla following either MRM or LAD. Drains were left in place until the preceding 24-hour drainage was
Databáze:	OpenAIRE
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