Multigram Scale Synthesis of A21, A New Antibiotic Equally Effective and Less Toxic than Amphotericin B
| Autor: | Ricardo Magaña, Mario Fernández-Zertuche, Iván Ortega-Blake, Josué Rodríguez-Lozada, Manuel López-Ortiz, Ignacio Regla, José David Flores-Romero |
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| Rok vydání: | 2016 |
| Předmět: |
Scale (ratio)
010405 organic chemistry Chemistry medicine.drug_class Stereochemistry Organic Chemistry Antibiotics Pharmacology bacterial infections and mycoses 010402 general chemistry Polyene 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Amphotericin B medicine Physical and Theoretical Chemistry medicine.drug |
| Zdroj: | Organic Process Research & Development. 20:1529-1532 |
| ISSN: | 1520-586X 1083-6160 |
| Popis: | A21 (2) is a new polyene macrolide Amphotericin B amide antibiotic derived from amphotericin B AmB (1), which has been tested extensively on preclinical trials showing the same antimycotic effectiv... |
| Databáze: | OpenAIRE |
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