Prehospital clopidogrel use and STEMI management: a review
| Autor: | Phillip Ebbs, Rachelle Hollier, Nathan Ross, Madison Sealy |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.drug_class Anticoagulant 030204 cardiovascular system & hematology medicine.disease Clopidogrel 03 medical and health sciences 0302 clinical medicine Emergency medicine medicine cardiovascular diseases 030212 general & internal medicine Myocardial infarction business circulatory and respiratory physiology medicine.drug |
| Zdroj: | Journal of Paramedic Practice. 13:1-10 |
| ISSN: | 2041-9457 1759-1376 |
| Popis: | Clopidogrel is an anticoagulant commonly used in the prehospital environment for the management of ST-elevation myocardial infarction (STEMI). Some ambulance services have incorporated this into their treatment regimens; however, others hold a variety of alternative pharmacological interventions. This study examines and determine the pharmacological efficacy and safety of clopidogrel in the management of patients with STEMI and assess whether ambulance services should use the drug as part of standard practice. A literature review was conducted to identify articles relating to the administration of clopidogrel in the prehospital setting. Fourteen peer-reviewed journal articles and eight clinical practice guidelines from international ambulance services were included in this review. According to this review, clopidogrel has been deemed safe, effective and practical for widespread use in the prehospital environment for the management of STEMI. However, some disagreement has arisen over whether clopidogrel is a more favourable anticoagulant than ticagrelor and prasugrel. Anticoagulants such as clopidogrel should be strongly considered as a standard treatment regimen in the prehospital management of STEMI across international jurisdictions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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