Effect of Different Doses of Inhaled Corticosteroids on the Isolation of Nasopharyngeal Flora in Children with Asthma
| Autor: | Shally Awasthi, Jyotsna Aggarwal, Sarika Gupta, Garima Nirmal |
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| Rok vydání: | 2019 |
| Předmět: |
Drug
Flora medicine.medical_specialty Isolation (health care) Inhalation business.industry media_common.quotation_subject Inhaled corticosteroids medicine.disease 03 medical and health sciences Dose–response relationship 0302 clinical medicine 030225 pediatrics Internal medicine Pediatrics Perinatology and Child Health Pediatric surgery medicine 030212 general & internal medicine business media_common Asthma |
| Zdroj: | Indian Pediatrics. 56:913-916 |
| ISSN: | 0974-7559 0019-6061 |
| Popis: | Objective To find the effects of inhaled corticosteroids and the impact of different doses of inhaled corticosteroids on the isolation of nasopharyngeal flora in asthmatic children aged 1-15 years. Methods The study included 75 children with asthma and 25 age-matched controls. Nasopharyngeal swabs were obtained. Bacteria were identified by standard techniques. Results Pathogenic organisms were isolated from 36% of asthmatic children and 20% of controls, the difference was not significant statistically (OR=2.25, 95% CI=0.75-6.67, P=0.13). There was no statistically significant association of using a high dose of inhaled corticosteroids with the isolation of pathogenic organisms. Usage of biomass fuel for cooking in the household of asthmatic children increases the risk of colonization (OR=3.4, 95% CI= 1.26-9.10, P=0.03). Conclusions Inhaled corticosteroids are safe in the treatment of asthma and there is no association between different doses of Inhaled corticosteroids and isolation of the pathogenic organism. |
| Databáze: | OpenAIRE |
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