Bone Maturnity Delay in Congenital Hypothyroid

Autor:	Azhari Gani, Iskandar Zakaria
Rok vydání:	2020
Předmět:	business.industry Incidence (epidemiology) Hormone biosynthesis Thyroid Physiology medicine.disease Iodine deficiency Thyroid dysgenesis Dysgenesis medicine.anatomical_structure Medicine Hormonal disorder business General Economics Econometrics and Finance
Zdroj:	Budapest International Research in Exact Sciences (BirEx) Journal. 3:726-734
ISSN:	2655-7827 2655-7835
DOI:	10.33258/birex.v3i1.1489
Popis:	Congenital hypothyroid (CH) is a Hormonal disorder that can be caused by thyroid gland dysfunction and if not treated early on, will cause serious mental and physical growth disorders. CH is divided into permanent and transient forms which etiologically can be divided into primary, secondary or peripheral. Thyroid dysgenesis is the primary cause and 85% of permanent CH is with abnormalities of thyroid hormone biosynthesis from birth (dishormongeneses). The incidence of dysgenesis accounts for 10-15% of cases. Transient congenital thyroid occurs mostly in infants with preterm birth in low-iodine endemic areas. A study showed a permanent incidence of CH 1: 1500 and transient CH 1: 300 in one of the areas with iodine deficiency in Central Java.Survival analysis showed that the risk of developing mental retardation and delayed physical growth was greater at the age of diagnosis over 1 year.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d6af9681cb8f36ccf948150c076195da https://doi.org/10.33258/birex.v3i1.1489 Zobrazit plný text záznamu