| Popis: |
Objective: The aim of this study was to investigate lupus anticoagulant (LA), anticardiolipin antibody (ACA), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) serum levels in 40 pregnant and 20 non-pregnant women. Materials and methods: The women were divided into three groups. The first group consisted of 20 pregnant women of less than 20 gestational weeks and with a past history of habitual abortion. The second group consisted of 20 non-pregnant patients with a past history of habitual abortion. The third group consisted of 20 healthy pregnant women. Result: LA was found in only one patient in Group 2. ACA IgG positivity was found in one patient in Group 1, three patients in Group 2 and one patient in Group 3. Mean ACA IgG was highest in Group 2. High serum TNF-α levels were found in 12 (60%), 6 (30%) and 2 (10%) women in Groups 1, 2 and 3, respectively. Conclusion: We propose that cytokines, especially TNF-α, were found to be related to pregnancy loss. |
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