ChemInform Abstract: On the Utility of S-Mesitylsulfinimines for the Stereoselective Synthesis of Chiral Amines and Aziridines

Autor:	Ian Churcher, Toni Moragas Solá, Heather Hobbs, Leonid Sasraku-Neequaye, Robert A. Stockman, David MacPherson, Caroline Roe
Rok vydání:	2011
Předmět:	chemistry.chemical_compound Chemistry Bromide organic chemicals Reagent heterocyclic compounds Stereoselectivity General Medicine Trimethylsulfonium iodide Combinatorial chemistry
Zdroj:	ChemInform. 42
ISSN:	0931-7597
DOI:	10.1002/chin.201146021
Popis:	The synthetic utility of S-mesitylsulfinimines for the synthesis of chiral amines and aziridines was examined through their reactions with Grignard reagents, with the ylides derived from trimethylsulfonium iodide and S-allyl-tetrahydrothiophenium bromide and through an aza-Darzens manifold, affording convenient access to a diverse range of highly substituted chiral amines and aziridines in high yields and excellent stereoselectivities.
Databáze:	OpenAIRE
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