Comparison of an electrochemiluminescent homogenous immunoassay and an ELISA for monitoring productivity in mammalian cell bioreactors
| Autor: | Tai-Guang Wu, Lee Hall, Charles L. Cooney, Per I. Lindell |
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| Rok vydání: | 1991 |
| Předmět: |
musculoskeletal diseases
Chromatography medicine.diagnostic_test medicine.drug_class Relative standard deviation Elisa assay Biology musculoskeletal system Monoclonal antibody Applied Microbiology and Biotechnology Biochemistry Molecular biology Immuno assay Mammalian cell Immunoassay Bioreactor medicine Product formation |
| Zdroj: | Biotechnology Techniques. 5:187-192 |
| ISSN: | 1573-6784 0951-208X |
| Popis: | An Enzyme Linked Immuno Sorbent Assays (ELISA) and an Electro-chemiluminescent Immuno Assay (CIA) are compared for the purpose of monitoring product formation in mammalian cell bioreactors. The ELISA had a relative standard deviation of 10%, compared to 8% for the CIA . The CIA was found to be a fast and accurate alternative to the ELISA. The use of more than one immuno assay format was also shown to provide additional insight into process performance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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