Microwave assisted synthesis of thiazolo[3,2-b][1,2,4]-triazoles containing 1,8-naphthyridine moiety

Autor: H. Sharath Babu, K. Mogilaiah, S. Kavitha, M. Prashanthi
Rok vydání: 2007
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 44:1161-1163
ISSN: 1943-5193
0022-152X
Popis: A simple and efficient protocol for the synthesis of 5-aryl-2-(2-substituted-1,8-naphthyridin-3-yl)-thiazolo[3,2-b][1,2,4]triazoles (4) is achieved by cyclocondensation of 3-(2-substituted-1,8-naphthyridin-3-yl)-1,2,4-triazoles (3) with α-halogenoketones in anhyd. methanol under microwave irradiation. The products are obtained in good yields and in a state of high purity.
Databáze: OpenAIRE