Microwave assisted synthesis of thiazolo[3,2-b][1,2,4]-triazoles containing 1,8-naphthyridine moiety
Autor: | H. Sharath Babu, K. Mogilaiah, S. Kavitha, M. Prashanthi |
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Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Journal of Heterocyclic Chemistry. 44:1161-1163 |
ISSN: | 1943-5193 0022-152X |
Popis: | A simple and efficient protocol for the synthesis of 5-aryl-2-(2-substituted-1,8-naphthyridin-3-yl)-thiazolo[3,2-b][1,2,4]triazoles (4) is achieved by cyclocondensation of 3-(2-substituted-1,8-naphthyridin-3-yl)-1,2,4-triazoles (3) with α-halogenoketones in anhyd. methanol under microwave irradiation. The products are obtained in good yields and in a state of high purity. |
Databáze: | OpenAIRE |
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