Observations on Chimpanzees after Whole-Body Radiation and Homologous Bone Marrow Treatment

Autor:	Eugene B. Blair, Harvey Rothberg, Wilbur Mcnulty, Alphonse C. Gomez
Rok vydání:	1959
Předmět:	Pathology medicine.medical_specialty Bone marrow transplantation Immunology Cell Biology Hematology Biology Biochemistry Acute radiation injury medicine.anatomical_structure medicine Homologous chromosome Bone marrow Whole body
Zdroj:	Blood. 14:1302-1321
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood.v14.12.1302.1302
Popis:	1. Three chimpanzees were given 900 r of whole body radiation followed by transfusion of homologous bone marrow. One animal survived for nearly six months. 2. Five chimpanzees were given 1200 r of whole body radiation; three of them were given homologous bone marrow. There was no difference in survival time of treated animals and of controls. 3. Observations were made on clinical, hematologic, bacteriologic and pathologic aspects of acute radiation injury. 4. There was no evidence of a "take" of the homologous marrow. The significance of the findings is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d68acb4a6cc1aaac00d96b5670610faa https://doi.org/10.1182/blood.v14.12.1302.1302 Zobrazit plný text záznamu