BIOPHYSICAL BASES OF GENOME ORGANIZATION

Autor: NP P Romanchuk, ES S Petrov, A N Volobuev
Rok vydání: 2017
Předmět:
Zdroj: Science and Innovations in Medicine. 2:13-17
ISSN: 2618-754X
2500-1388
DOI: 10.35693/2500-1388-2017-0-4-13-17
Popis: Aim - the analysis of nucleotide sequences of DNA molecules and the bases of the information storage with the help of DNA. Material and methods - the study is based on Markov chain theory and Bayesian Information Criterion. Results. Principles of genetic code construction were investigated. Specific nucleotide sequences were analyzed using Markov chain theory; the method of sequencing nucleotide sequences was described. Conclusion. A nucleotide sequence has certain restrictions associated with complementarity of the bases along DNA chain. These restrictions at the level of triplet sequence can be eliminated by degeneracy of the genetic code.
Databáze: OpenAIRE