Surface Properties of Alginate/Chitosan Biofilm for Wound Healing Application
| Autor: | Siti Natrah Abdul Bakil, Mohammed Firdaus Adzhari, T.C. Lee, Mohamad Ali Selimin, Maizlinda Izwana Idris, Hasan Zuhudi Abdullah |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Fabrication
Materials science Mechanical Engineering Biofilm Alginate chitosan engineering.material Condensed Matter Physics Contact angle Chitosan chemistry.chemical_compound Chemical engineering chemistry Mechanics of Materials Surface roughness engineering General Materials Science Biopolymer Wound healing |
| Zdroj: | Materials Science Forum. 1010:602-607 |
| ISSN: | 1662-9752 |
| Popis: | This work focuses on the fabrication of film based on natural biopolymers for wound healing application. Alginate and chitosan were choosen because of their oustanding properties such as biocompatible, hydrophilic and non-toxic. Earlier, the biopolymer film was fabricated by using alginate 1% wt and chitosan 1% wt. solutions at volume ratios of 99:1 and 97:3. Next, the biopolymer film solution was cross-linked with 1M CaCl2.2H2O for two hours and later dried for 24 hours at room temperature. Then, the surface properties of the prepared biopolymer films were characterised via Field Emission Scanning Electron Microscopy (FESEM), Atomic Force Microscopy (AFM) and contact angle measurement. It was observed that the surface of the biopolymer film became rougher as the volume of the chitosan increases. This condition was confirmed with average surface roughness, RA for biopolymer film with ratio of 97:3 resulted in higher values. Also it was found that the surface of biopolymer films were hydrophilic after the contact angle was less than 90°. This can be concluded that the biopolymer based on alginate/chitosan is a promising candidate for wound healing materials particularly with good surface properties for faster healing process at the wound areas. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|