Synthesis of 2-Hydroxy-8'-(hydroxymethyl)-1,1'-binaphthalene (iso-Homo-BINOL). A New Structural Pattern in the Binaphthyl Realm

Autor:	Pavel Kočovský, Stephen C. Lockhart, Štěpán Vyskočil, William L. Mitchell
Rok vydání:	2003
Předmět:	chemistry.chemical_compound chemistry Suzuki reaction Bromide Stereochemistry NOBIN Hydroxymethyl General Chemistry Phenols Enantiomer Carbonylation
Zdroj:	Collection of Czechoslovak Chemical Communications. 68:907-916
ISSN:	1212-6950 0010-0765
DOI:	10.1135/cccc20030907
Popis:	The title compound 7 has been synthesized in a racemic form, using Suzuki coupling (8 + 15 → 16) as the key step. Pure enantiomer (S)-(-)-7 has been obtained by carbonylation of the known bromide (S)-(+)-12 followed by reduction of the resulting methyl ester (S)-(+)-18 with LiAlH4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d67da3aa2b5254caae87ab1e76141e77 https://doi.org/10.1135/cccc20030907 Zobrazit plný text záznamu