Experimental photodynamic therapy: 15 years of development

Autor:	Nataliya I. Kazachkina, A. V. Butenin, Marina G. Strakhovskaya, E. A. Plotnikova, B. Ya. Kogan, Valery I. Chissov, T. N. Andreeva, Yu. B. Venediktova, A. A. Pankratov, Tatyana Karmakova, Raisa I. Yakubovskaya, Anna D. Plyutinskaya, E. V. Filonenko, Victor V. Sokolov, E. R. Nemtsova, N. B. Morozova, Alexey V. Feofanov
Rok vydání:	2015
Předmět:	Oncology medicine.medical_specialty Chemotherapy Chemistry medicine.medical_treatment Cancer Photodynamic therapy General Chemistry medicine.disease In vivo Internal medicine medicine Medical physics Combined method
Zdroj:	Russian Journal of General Chemistry. 85:217-239
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363215010405
Popis:	Photodynamic therapy and fluorescence diagnosis of malignant tumors have been actively developed over the last 15 years by the scientists participating in the Moscow Government-funded “Fight against Cancer” program. New effective photosensitizers absorbing in the long-wave spectral region were revealed. Unique agents Alasens-lio, Alasens-gel, Hexasens-lio, Phthalosens-lio, Holosens-lio, and Holosensgel were produced and preclinically studied both in vitro and in vivo. New methods using low-intensity and pulse modes of irradiation and also combined methods of treatment by photodynamic therapy and well-known chemotherapy or laser hyperthermia were developed. Methodological recommendations for experimental studies of agents with photoinduced antitumor properties were published.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d674c5332d0d956a3ba113515a9fac80 https://doi.org/10.1134/s1070363215010405 Zobrazit plný text záznamu Plný text ve formátu PDF