Association analysis of the INHA gene with litter size in Boer goats

Autor: Chunyan Zhang, Weisheng Wu, Khairy M.A. Zoheir, Guohua Hua, Shi-Lin Chen, Qunying Wen, Liguo Yang
Rok vydání: 2009
Předmět:
Zdroj: Small Ruminant Research. 82:139-143
ISSN: 0921-4488
DOI: 10.1016/j.smallrumres.2009.01.005
Popis: This study investigated the association between differences in litter size in Boer does, with genetic polymorphisms in the inhibin alpha gene. Our preliminary (n = 209) results found 12 SNPs, including the non-synonymous polymorphisms 911T/C and 946A/C, resulting in corresponding 299V/A and 311T/P amino acid polymorphisms. Of the SNPs, 651A/G was preliminarily suggested as a useful marker for litter size of the second parity in the population studied, showing an overdominance effect. Polymorphisms, sequence, and genotype distributions were also characterized. © 2009 Published by Elsevier B.V.
Databáze: OpenAIRE