Prevention of deteriorations of blood biochemical indices in experimental stress in rats
| Autor: | T. V. Momot, Yu. A. Rakhmanin, N F Kushnerova |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Phosphatidylethanolamine
medicine.medical_specialty Chemistry Cholesterol Health Toxicology and Mutagenesis Hypertriglyceridemia Public Health Environmental and Occupational Health Lipid metabolism General Medicine Glutathione 030204 cardiovascular system & hematology medicine.disease Pollution 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Blood serum Dry weight Internal medicine Phosphatidylcholine medicine 030211 gastroenterology & hepatology |
| Zdroj: | Hygiene and sanitation. 95:678-681 |
| ISSN: | 2412-0650 0016-9900 |
| DOI: | 10.18821/0016-9900-2016-95-7-678-681 |
| Popis: | Results of the research of the impact of extract from the byproducts of guelder-rose, containing a complexflavonoides (65% of dry weight), in the conditions of experimental a stress (vertical fixing of rats by a dorsal cervicalfold for 22 o’clock) are presented. The impact of a stress was shown to be followed by the gain in mass of adrenal glands by 42%. In blood serum there were noted marked hypertriglyceridemia, hypercholesterolemia, increased superoxide dismutase activity, decline in the number of reduced glutathione and anti-radical activity, the gain in lisofractions of phospholipids, decrease of phosphatidylcholine, phosphatidylethanolamine, cholesterol esters. Administration of the extract from the byproducts of guelder rose crushing promoted the normalization of indices of mass of adrenal glands and lipid metabolism in blood serum, was more effective, than a reference stress protector “Extract eleuterokokka®”. The introduction of eleuterococcus was followed by the persistent both elevated level of cholesterol, free fatty acids, lisofraction of phospholipidsand low level offatty acids esters, cholesterol esters and a diphosphatidilglicerin. Byproducts of guelder-rose were shown to represent a perspective view of raw materials for the producing of stress protective preparations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|