Mechanismen des nicht konventionellen RNA-Spleißens
Autor: | Jirka Peschek |
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Rok vydání: | 2021 |
Předmět: |
0303 health sciences
Rna processing Chemistry Endoplasmic reticulum 030302 biochemistry & molecular biology Pharmacology toxicology RNA Cell biology 03 medical and health sciences chemistry.chemical_compound Biosynthesis RNA splicing TRNA maturation Molecular Biology 030304 developmental biology Biotechnology |
Zdroj: | BIOspektrum. 27:233-236 |
ISSN: | 1868-6249 0947-0867 |
DOI: | 10.1007/s12268-021-1560-1 |
Popis: | The cellular pool of RNA is immensely diverse and complex. During their biosynthesis, RNA molecules undergo a vast number of co- and posttranscriptional processing and modification steps. A unique example of RNA processing is the non-conventional splicing of RNAs. This protein-catalysed splicing mechanism is an essential step during tRNA maturation and a main mode of endoplasmic reticulum (ER) stress signalling. Here, I discuss the cellular roles and catalytic machinery of non-conventional splicing in eukaryotes. |
Databáze: | OpenAIRE |
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