Platelet Consumption in Thrombocythemia Complicated by Erythromelalgia: Reversal by Aspirin
| Autor: | Lindemans J, van Strik R, van Vliet Hh, van Genderen Pj, Jan Jacques Michiels |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Pathology
medicine.medical_specialty Chemotherapy Aspirin business.industry Vascular disease medicine.medical_treatment Hematology medicine.disease Asymptomatic Gastroenterology Erythromelalgia hemic and lymphatic diseases Internal medicine Medicine Platelet Polycythemia rubra vera medicine.symptom business Complication medicine.drug |
| Zdroj: | Thrombosis and Haemostasis. 73:210-214 |
| ISSN: | 2567-689X 0340-6245 |
| DOI: | 10.1055/s-0038-1653752 |
| Popis: | SummaryThe involvement of platelets in the pathogenesis of erythromelalgia, a frequent and characteristic microvascular thrombotic manifestation in patients with primary thrombocythemia and polycythemia rubra vera, was investigated by measuring the survival and turnover of 51Cr labeled autologous platelets in 10 patients with thrombocythemia complicated by erythromelalgia, in 10 asymptomatic thrombocythemia patients and in 6 subjects with reactive thrombocytosis. The mean platelet survival time of the erythromelalgia patients was 4.2 ± 0.2 days, which is significantly decreased as compared with asymptomatic thrombocythemia patients (6.6 ± 0.3 days, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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