Indirect determination of sodium diclofenac, sodium dipyrone and calcium gluconate in injection drugs using digital image-based (webcam) flame emission spectrometric method

Autor:	Edvan Cirino da Silva, Paulo Henrique Gonçalves Dias Diniz, Francisco Antônio da Silva Cunha, Fátima Aparecida Castriani Sanches, Mário César Ugulino de Araújo, Wellington da Silva Lyra, Sherlan G. Lemos
Rok vydání:	2011
Předmět:	General Chemical Engineering General Engineering Analytical chemistry chemistry.chemical_element Diclofenac Sodium Calcium Analytical Chemistry Digital image chemistry Linear range Calibration RGB color model Figure of merit Sodium dipyrone
Zdroj:	Analytical Methods. 3:1975
ISSN:	1759-9679 1759-9660
DOI:	10.1039/c1ay05197k
Popis:	This paper proposes a digital image-based flame emission spectrometric (DIB-FES) method for indirect determination of sodium diclofenac, sodium dipyrone and calcium gluconate in injectable forms. The proposed DIB-FES method uses digital images obtained from a webcam, based on the RGB (Red-Green-Blue) system. It offers a simple and inexpensive way to quantify these organic substances using the radiation emitted by the alkaline and earth-alkaline metals present in their formulae. Analytical curves were constructed on the basis of the relationship between RGB values and calibration solution concentrations. The results showed no statistical difference between the proposed and reference methods when applying the paired t-test at a 95% confidence level. The proposed DIB-FES method also performed well in terms of the figures of merit LOD, LOQ, linear range, precision, and the accuracy as revealed by recovery tests.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d61504f8d7e6083e990cb818c3c6fd55 https://doi.org/10.1039/c1ay05197k Zobrazit plný text záznamu