Effect on the Infection with Chondrococcus and Chronic Oral Toxicity of Furpyridinol(P-7138)in Goldfish

Autor:	Kaoru Kouno, Shinsuke Ose, Masanao Shimizu, Yoshiyuki Takase
Rok vydání:	1968
Předmět:	Drug Chondrococcus media_common.quotation_subject Aquatic Science Biology Pharmacology In vitro Oral administration Immunology medicine Animal Science and Zoology Oral toxicity medicine.symptom Antibacterial activity Survival rate Weight gain media_common
Zdroj:	Fish Pathology. 3:5-11
ISSN:	1881-7335 0388-788X
DOI:	10.3147/jsfp.3.5
Popis:	Goldfish were fed with diets containing 0.02%and 0.002% of Furpyridinol(P-7138)for 120days. Compared with the control group, the medicated groups did not show any unfavourable effects on survival rate, weight gain, behavior, etc. During the experiments the infection with chondrococcus occurred in the control group. However, no infection was observed in the medicated groups. These results suggested that the oral administration of this drug, which showed high antibacterial activity in vitro against chondrococci(MIC:0.003-0.01mcg/ml), might prevent the infection with chondrococci in goldfish.
Databáze:	OpenAIRE
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