Abstract PS1-20: Pathologic lymph lode status of patients with T1 HER2-positive breast cancer who did not receive neoadjuvant chemotherapy using the national cancer database
| Autor: | Claudia B. Perez, Rosalinda Alvarado, Andrea Madrigrano, Neha Nimmagadda, Cristina O'Donoghue, Laura DeCesare, Yanyu Zhang, Nicholas J. Skertich, Aaron L. Wiegmann, Samantha Terranella |
|---|---|
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Cancer Research. 81:PS1-20 |
| ISSN: | 1538-7445 0008-5472 |
| Popis: | Purpose: HER2 directed neoadjuvant therapies for locally advanced HER2-positive breast cancer have improved complete pathologic response and event-free survival. For T1 breast cancer, lymph node status often determines whether neoadjuvant treatment is indicated. The aim of this study was to identify patient and tumor characteristics using the National Cancer Database.Methods: A retrospective review of patents diagnosed with T1 clinically node negative (cT1N0) HER2-positive breast cancers was performed using the American College of Surgeons National Cancer Database (ACS NCDB) from 2004-2016. Exclusion criteria included age Results: A total of 57,366 T1 HER2-positive patients were identified with 8,994 patients (15.68%) having positive lymph nodes. Characteristics associated with lymph node involvement included age (p Citation Format: Laura DeCesare, Claudia Perez, Neha Nimmagadda, Yanyu Zhang, Samantha Terranella, Nicholas Skertich, Aaron Wiegmann, Andrea Madrigrano, Rosalinda Alvarado, Cristina O'Donoghue. Pathologic lymph lode status of patients with T1 HER2-positive breast cancer who did not receive neoadjuvant chemotherapy using the national cancer database [abstract]. In: Proceedings of the 2020 San Antonio Breast Cancer Virtual Symposium; 2020 Dec 8-11; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2021;81(4 Suppl):Abstract nr PS1-20. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|