Preparation of monoclonal antibodies against human thyrotropin suitable for diagnostic systems and their use in clinical practice

Autor:	L. K. Koryazova, E. N. Petrova, R. G. Vasilov, E. R. Sigal, V. E. Samoilova, T. A. Pozdnyakova, G. I. Kovalevskaya
Rok vydání:	1994
Předmět:	biology medicine.diagnostic_test medicine.drug_class business.industry General Medicine Diagnostic system Monoclonal antibody General Biochemistry Genetics and Molecular Biology Clinical Practice Antigen Immunoassay Immunology medicine biology.protein Antibody business
Zdroj:	Bulletin of Experimental Biology and Medicine. 118:1133-1135
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02446478
Popis:	Original methods are presented for immunizing mice with preparations of human thyrotropic and for testing primary clones of producer hybridomas. Twelve monoclonal antibodies specific to six different regions of the antigen are obtained. A test system for enzyme immunoassay is developed on the basis of two antibodies, providing for detection of hypo- and hyperthyreoidism in clinical practice.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d60ba9b9fd90b01cef81ec068efa020b https://doi.org/10.1007/bf02446478 Zobrazit plný text záznamu Full text from SpringerLink